ABC proteins

ABC proteins
Membrane proteins involved in active transport or regulation of ion channel function and having an ATP binding cassette. Most examples are prokaryotic, but important eukaryotic examples are the P-glycoprotein (multidrug resistance transporter), the cystic fibrosis transmembrane conductance regulator (CFTR), and SUR.

Dictionary of molecular biology. 2004.

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  • ABC transporters — [ATP binding cassette] a large family of transport proteins, consisting of two transmembrane and two cytoplasmic domains, that use energy released by ATP hydrolysis to transport a variety of substances across cell membranes …   Medical dictionary

  • ATP-binding domain of ABC transporters — Pfam box Symbol = ABC tran Name = width = caption =Multidrug ABC transporter SAV1866, closed state Pfam= PF00005 InterPro= IPR003439 SMART= PROSITE = PDOC00185 SCOP = 1b0u TCDB = 3.A.1 OPM family= 17 OPM protein=2hyd PDB=PDB3|1vplA:29 210… …   Wikipedia

  • Transmembrane domain of ABC transporters — Pfam box Symbol = ABC membrane Name = ABC transporter transmembrane region width = caption = Pfam= PF00664 InterPro= IPR001140 SMART= PROSITE = PDOC00364 SCOP = 1pf4 TCDB = 3.A.1 OPM family= 18 OPM protein= 1pf4 PDB=ABC transporter transmembrane… …   Wikipedia

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  • P-glycoprotein — ATP binding cassette, sub family B (MDR/TAP), member 1 Crystallographic structure of the mouse MDR3 protein. The approximate positioning of the protein in the cell membrane is indicated by the blue (extracellular face) and red (cytoplasmic face)… …   Wikipedia

  • ABCG2 — ATP binding cassette, sub family G (WHITE), member 2 Identifiers Symbols ABCG2; ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; MGC102821; MRX; MXR; MXR1 External IDs …   Wikipedia

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